There has been much written on Slaw and other places about the paperless office, or the virtual office.
My personal view is that for the most part, we either already have the tools to accomplish it, or if we don't have them, they can be acquired at low cost. The barrier is mostly our will to do it. Some people don't see the need, or have a hard time giving up paper, or just find it hard to change.
Technolawyer points to an article that's worth a read by New York lawyer Jay Fleishman entitled Being a Virtual Lawyer is all Mindset, not Technology. While the article talks about the virtual office, the same goes for the paperless office, as a paperless office is essentially a virtual office that stays in one place.
For the record, I'm not totally paperless yet, but I'm getting close. Perhaps I just need to take a few minutes to think about the paper that still flows through my office, and decide how to deal with it.