Dan’s 10 essential technology skills and practices contains some good tips (although I must admit I’m not good with keyboard shortcuts – I think more graphically and tend to use the mouse).
I have a couple more to add.
When creating Word documents don’t use the “enter” key to create spaces between paragraphs. The right way is to use the paragraph settings to set the “before and after” spacing. Otherwise, you can’t make efficient use of things like paragraph numbering or bullets. And by using the “before and after” setting, you can often easily adjust the length of a document . . . [more]